N'ihe gbasara sayensị ịchọ mma, DL panthenol dị ka isi igodo na-emeghe ụzọ maka ahụike akpụkpọ ahụ. Ihe mmalite a nke vitamin B5, nke nwere ezigbo mmiri mmiri, nrụzi na mmetụta mgbochi mkpali, aghọwo ihe dị mkpa na-arụ ọrụ na usoro nlekọta anụ ahụ. Edemede a ga-enyocha ihe omimi sayensị, uru ngwa yana atụmanya DL panthenol n'ọdịnihu.
1. Sayensị decoding nkeDL panthenol
DL panthenol bụ ụdị agbụrụ panthenol, nke nwere aha kemịkal 2,4-dihydroxy-N - (3-hydroxypropyl) -3,3-dimethylbutanamide. Usoro ihe omimi ya nwere otu mmanya na-aba n'anya na otu mmanya abụọ nke abụọ, nke na-enye ya nnukwu hydrophilicity na permeability.
Usoro ntughari na akpụkpọ ahụ bụ isi ihe na-arụ ọrụ nke DL panthenol. Mgbe ịbanye n'ime akpụkpọ ahụ, DL panthenol na-agbanwe ngwa ngwa ka ọ bụrụ pantothenic acid (vitamin B5), nke na-ekere òkè na njikọ nke coenzyme A, si otú ahụ na-emetụta abụba acid metabolism na cell proliferation. Nnyocha egosiwo na ngbanwe nke DL panthenol na epidermis nwere ike iru 85%.
Isi usoro nke ime ihe na-agụnye ịkwalite ọrụ mgbochi akpụkpọ ahụ, ịkwalite mgbasa nke cell epithelial, na igbochi nzaghachi mkpali. Data nnwale na-egosi na mgbe ejiri ngwaahịa nwere 5% DL panthenol maka izu anọ, mfu mmiri transdermal nke akpụkpọ ahụ na-ebelata site na 40%, na iguzosi ike n'ezi ihe nke stratum corneum na-abawanye nke ọma.
2, Multidimensional ngwa nkeDL panthenol
N'ihe gbasara moisturize, DL panthenol na-eme ka hydration nke stratum corneum dịkwuo elu ma na-abawanye ọdịnaya mmiri anụ ahụ. Nnwale ụlọọgwụ egosila na iji moisturizer nwere DL panthenol maka awa 8 na-abawanye ọdịnaya mmiri anụ ahụ site na 50%.
N'ihe gbasara nrụzi, DL panthenol nwere ike ịkwalite mmụba cell epidermal ma mee ka ọrụ mgbochi rụọ ọrụ ngwa ngwa. Nnyocha egosila na iji ngwaahịa nwere DL panthenol eme ihe mgbe arụchara ọrụ ahụ nwere ike belata oge ọgwụgwọ ọnya site na 30%.
Maka nlekọta anụ ahụ nwere mmetụta, DL panthenol na-egbochi mkpali na mmetụta dị nro bụ nke a ma ama. Nnwale egosiwo na DL panthenol nwere ike igbochi ntọhapụ nke ihe ndị na-egbuke egbuke dị ka IL-6 na TNF-α, na-ebelata akpụkpọ anụ ahụ na-acha uhie uhie na mgbakasị ahụ.
Na nlekọta ntutu isi, DL panthenol nwere ike banye n'ime ntutu ma mezie keratin mebiri emebi. Mgbe ejirichara ngwaahịa nlekọta ntutu isi nwere DL panthenol maka izu iri na abụọ, ike mgbaji ntutu mụbara site na 35% na nchapụta wee na-abawanye site na 40%.
3. Atụmanya ọdịnihu nke DL panthenol
Teknụzụ mmepụta ọhụrụ dị ka nanocarriers na liposomes emeela ka nkwụsi ike na bioavailability nke ọma dịkwuo mma.DL panthenol. Dịka ọmụmaatụ, nanoemulsions nwere ike ịbawanye ike nke DL panthenol site na ugboro abụọ.
Nnyocha ngwa ụlọ ọgwụ na-aga n'ihu na-amụbawanye. Nnyocha ọhụrụ a na-egosi na DL panthenol nwere uru ọ bara na ọgwụgwọ adjuvant nke ọrịa anụ ahụ dị ka atopic dermatitis na psoriasis. Dịka ọmụmaatụ, iji DL panthenol nwere usoro n'ime ndị ọrịa nwere atopic dermatitis nwere ike ibelata akara itching site na 50%.
Atụmanya ahịa ahụ sara mbara. A na-atụ anya na n'afọ 2025, nha ahịa DL panthenol zuru ụwa ọnụ ga-eru nde dollar US 350, yana mmụba kwa afọ karịa 8%. Site na mmụba na-abawanye maka ihe ndị na-arụ ọrụ dị nro sitere n'aka ndị na-azụ ahịa, mpaghara ngwa nke DL panthenol ga-agbasawanye.
Nchọpụta na ntinye nke DL panthenol emeghela oge ọhụrụ maka nlekọta anụ ahụ. Site na moisturizing na nrụzi ka mgbochi mkpali na obi iru ala, site na ihu na-elekọta anụ ahụ, a multifunctional mgwa na-agbanwe anyị echiche banyere ahụ ike akpụkpọ. N'ọdịnihu, na ọganihu nke nkà na ụzụ mmepụta ihe na ime nnyocha nyocha ụlọ ọgwụ, DL panthenol ga-eme ka ihe ọhụrụ na ohere maka nlekọta anụ ahụ dịkwuo mma. N'ụzọ nke ịchụso ịma mma na ahụike, DL panthenol ga-anọgide na-arụ ọrụ ya pụrụ iche na nke dị mkpa, na-ede akwụkwọ ọhụrụ na sayensị akpụkpọ anụ.
Oge nzipu: Mar-18-2025
